What medicine should be used for pain after surgery?
Postoperative pain is one of the common postoperative complications for patients. Proper use of analgesics can not only relieve pain, but also promote recovery. This article will combine the hot topics and hot content on the Internet in the past 10 days to provide you with a detailed introduction to medication selection, precautions and the latest research progress for post-operative pain.
1. Common drugs for post-operative pain

The choice of medication for post-operative pain needs to be comprehensively determined based on the degree of pain, the patient’s constitution and the type of surgery. The following are the classification and characteristics of common postoperative analgesic drugs:
| drug type | Representative medicine | Applicable pain level | Things to note |
|---|---|---|---|
| Nonsteroidal anti-inflammatory drugs (NSAIDs) | Ibuprofen, acetaminophen | mild to moderate pain | May cause gastrointestinal discomfort, long-term use requires caution for liver and kidney damage |
| Opioids | Morphine, Oxycodone | moderate to severe pain | Easy to become addicted, please strictly follow doctor’s instructions when using it. |
| local anesthetic | lidocaine, ropivacaine | local pain | Commonly used for incision analgesia with fewer side effects |
| adjuvant analgesics | Gabapentin, pregabalin | neuropathic pain | Be aware of side effects such as drowsiness and dizziness |
2. Hot topics on the Internet: New trends in post-operative analgesia
In the past 10 days, discussions about post-operative analgesia have mainly focused on the following aspects:
1.multimodal analgesia: Combining drugs with different mechanisms (such as NSAIDs + opioids + local anesthesia) to reduce the side effects of a single drug has become a clinically recommended solution.
2.non-drug therapy: Acupuncture, physical therapy and other auxiliary methods have been mentioned many times, especially for patients who are sensitive to drugs.
3.personalized medicine: The topic of genetic testing to guide the selection of painkillers has become more popular, and some hospitals have launched pilot projects.
3. Medication precautions
1.Follow doctor's advice: Opioids need to be used strictly according to the dosage and avoid increasing or decreasing on your own.
2.Monitoring of side effects: If nausea, constipation (common in opioids) or rash (allergy to NSAIDs) occurs, seek medical attention promptly.
3.Avoid duplication of medications: Some compound cold medicines contain acetaminophen. Please note that the total dose does not exceed the daily limit (usually 4g for adults).
4. Latest research progress
| research topic | Core findings | Data source |
|---|---|---|
| Postoperative pain management AI model | Machine learning can predict patient pain levels with 89% accuracy | "Nature" sub-journal (2024.5) |
| New sustained-release analgesic patch | A single application continuously releases lidocaine for 72 hours | Approved by US FDA (2024.6) |
5. Summary
Postoperative pain medication needs to be selected individually. For mild pain, NSAIDs can be tried first, while for moderate to severe pain, opioids need to be used under the guidance of a doctor. Combined with the hot discussion trend across the Internet, multi-modal analgesia and personalized solutions will become the mainstream in the future. Patients should pay close attention to drug side effects and actively cooperate with non-drug therapies to speed up recovery.
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